A 14-year-old boy presents to the physician with recurrent pyogenic infections. Physical examination shows that the boy has pruritic papulovesicular d

Subject
Paediatrics
System
Dermatology

Kathryn

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Jul 29, 2020
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A 14-year-old boy presents to the physician with recurrent pyogenic infections. Physical examination shows that the boy has pruritic papulovesicular dermatitis. Blood is drawn and sent for laboratory evaluation of platelets and immunoglobulin levels. The results show a markedly low platelet count, a low serum IgM level, and an elevated IgA level. This patient most likely has which of the following conditions?
(A) Bruton’s agammaglobulinemia
(B) Chédiak-Higashi disease
(C) Job’s syndrome
(D) Thymic aplasia
(E) Wiskott-Aldrich syndrome
 
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