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A 2-year-old girl is brought to the ED because of fevers that have been occurring daily for 3 weeks. Physical examination reveals a 1.2-kg (2.6-lb) weight loss since her last doctor’s visit 1 month earlier. She also has pallor, hepatomegaly, and splenomegaly. She is admitted to the hospital and undergoes bone marrow aspiration; results are shown in the image. Which of the following is the most likely diagnosis?
(A) Acute lymphoblastic leukemia
(B) Ewing’s sarcoma
(C) Hemophagocytic lymphohistiocytosis
(D) Neuroblastoma
(E) Wilms’ tumor
A 2-year-old girl is brought to the ED because of fevers that have been occurring daily for 3 weeks. Physical examination reveals a 1.2-kg (2.6-lb) weight loss since her last doctor’s visit 1 month earlier. She also has pallor, hepatomegaly, and splenomegaly. She is admitted to the hospital and undergoes bone marrow aspiration; results are shown in the image. Which of the following is the most likely diagnosis?
(A) Acute lymphoblastic leukemia
(B) Ewing’s sarcoma
(C) Hemophagocytic lymphohistiocytosis
(D) Neuroblastoma
(E) Wilms’ tumor
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