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A 22-year-old woman presents with a fusiform swelling of the Achilles tendon, which, when biopsied, shows cholesterol-laden macrophages (foam cells) dispersed among the collagen fibers. She had been troubled with joint pains for several years. Both her mother and father developed arthritis associated with production of xanthomas, but their first symptoms occurred in middle age. She was referred to a nutritionist and treated with an enzyme inhibitor. Which of the following is most likely elevated in the blood of this woman?
(A) Chylomicron remnants
(B) Chylomicrons
(C) High density lipoproteins (HDL)
(D) Low density lipoproteins (LDL)
(E) Very low density lipoproteins (VLDL)
A 22-year-old woman presents with a fusiform swelling of the Achilles tendon, which, when biopsied, shows cholesterol-laden macrophages (foam cells) dispersed among the collagen fibers. She had been troubled with joint pains for several years. Both her mother and father developed arthritis associated with production of xanthomas, but their first symptoms occurred in middle age. She was referred to a nutritionist and treated with an enzyme inhibitor. Which of the following is most likely elevated in the blood of this woman?
(A) Chylomicron remnants
(B) Chylomicrons
(C) High density lipoproteins (HDL)
(D) Low density lipoproteins (LDL)
(E) Very low density lipoproteins (VLDL)
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