A 26-year-old G1P0 woman at 12 weeks’ gestation presents to her obstetrician for her first visit. Her pregnancy thus far has been notable only for som

Subject
Obstetrics and Gynaecology
System
Pregnancy, Childbirth & Puerperium

Kathryn

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Jul 29, 2020
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A 26-year-old G1P0 woman at 12 weeks’ gestation presents to her obstetrician for her first visit. Her pregnancy thus far has been notable only for some mild nausea and vomiting that lasted throughout her first trimester. She reports feeling overly tired lately and very weak. Her past medical history is significant for pernicious anemia. On physical examination she is an anxious-appearing, thin woman. Her blood pressure is 130/85 mm Hg, heart rate is 115/ min, and respiratory rate is 18/min. Fetal heart tones are present at 135/min. The uterine fundus is at 12 cm. The woman has a diffuse, non- tender goiter, a resting tremor, and poor global muscle strength. Which is the most likely mechanism underlying this woman’s condition?
(A) Autoantibodies against thyroid-stimulating hormone receptor
(B) Iodine overdose
(C) The mechanism of this disease is unknown
(D) Uncontrolled cell growth
(E) Viral infection
 
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