A 27-year-old man visits his primary care physician for a routine check-up. He has no medical history and has started working in a hospital 6 months ago. As a health screen, he needs a purified protein derivative (PPD) test and an HIVtest. Three days later, the PPD site is in durated. He has never been given the Bacille Calmette-Guerin (BCG) vaccine.Which of the following features would tend to argue against chemoprophylaxis with isoniazid?
A. Exposure to a patient with active tuberculosis
B. HIV positive, induration of 5 mm
C. HIV negative, induration of 4 mm
D. Negative PPD 1 year earlier
E. Positive PPD 1 year earlier
A. Exposure to a patient with active tuberculosis
B. HIV positive, induration of 5 mm
C. HIV negative, induration of 4 mm
D. Negative PPD 1 year earlier
E. Positive PPD 1 year earlier