#february2020mccqe1
A 30-year-old man presents with a rapidly enlarging, single, stony hard, palpable 2.5-cm nodule in his thyroid gland. Thyroid isotope scanning demonstrates the nodule to be “cold.” On resection of the thyroid gland with subsequent pathologic examination, the nodule is found to contain follicular structures, some of which have inwardly protruding fibrovascular branching cores covered by epithelial cells. Many of the epithelial cells have “orphan Annie” nuclei. Which of the following is the most likely diagnosis?
(A) Follicular carcinoma of the thyroid
(B) Graves disease
(C) Hashimoto disease
(D) Nontoxic goiter
(E) Papillary carcinoma of the thyroid
A 30-year-old man presents with a rapidly enlarging, single, stony hard, palpable 2.5-cm nodule in his thyroid gland. Thyroid isotope scanning demonstrates the nodule to be “cold.” On resection of the thyroid gland with subsequent pathologic examination, the nodule is found to contain follicular structures, some of which have inwardly protruding fibrovascular branching cores covered by epithelial cells. Many of the epithelial cells have “orphan Annie” nuclei. Which of the following is the most likely diagnosis?
(A) Follicular carcinoma of the thyroid
(B) Graves disease
(C) Hashimoto disease
(D) Nontoxic goiter
(E) Papillary carcinoma of the thyroid
