QBANK A 38 year-old woman presents with shortness of breath and cough productive of blood-tinged sputum. Patient has been unresponsive to antibiotic therapy

[DianaZ]

A 38 year-old woman presents with shortness of breath and cough productive of blood-tinged sputum. Patient has been unresponsive to antibiotic therapy but showed some improvement on corticosteroid therapy. She is febrile, blood pressure 124/82 mmHg, pulse 74 and respiratory rate of 19/min. Laboratory studies reveal an erythrocyte sedimentation rate (ESR) of 90/min, anemia, and circulating anti-neutrophil cytoplasmic antibodies of c-ANCA type. Urinalysis indicates
dysmorphic red cells and red cell casts. Which of the following antibodies is most likely to be found in the patient's serum?

A. Anti-Proteinase-3
B. Anti-Myeloperoxidase
C. Anti-Centromere
D. Anti-dsDNA
E. Anti-mitochondria