A 52-year-old woman from Southeast Asia comes to medical attention because of slowly growing nodular lesions on her nose and auricles. Examination als

Subject
Medicine
System
Dermatology, Infectious Diseases

Kathryn

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Jul 29, 2020
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A 52-year-old woman from Southeast Asia comes to medical attention because of slowly growing nodular lesions on her nose and auricles. Examination also reveals bilateral hypoesthesia in the upper extremities along the ulnar nerve distribution. Biopsies of the skin lesions demonstrate a florid granulomatous reaction with numerous acid-fast bacilli (AFB) within multinucleated giant cells. Cultures on blood agar and special media, however, yield no growth. Which of the following is the most likely diagnosis?
(A) Lepromatous leprosy
(B) Lupus vulgaris
(C) Mycobacterium avium-intracellulare (MAI)
(D) Sarcoidosis
(E) Tuberculoid leprosy
 
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