A 61-year-old obese man with a history of chronic alcohol abuse is diagnosed with type 2 DM. In addition to diet modification and exercise, his physic

Subject
Medicine
System
Endocrine, Diabetes & Metabolism

Kathryn

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Jul 29, 2020
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A 61-year-old obese man with a history of chronic alcohol abuse is diagnosed with type 2 DM. In addition to diet modification and exercise, his physician recommends he begin therapy with a hyperglycemic agent. Several days after starting therapy, his wife comes home from work and finds him sitting on the couch staring into space and breathing rapidly. When she speaks to him, she finds he is quite confused, and immediately takes him to the emergency department. Arterial blood gas analysis shows:
pH: 7.2
HCO3−: 19 mEq/L 3
Partial carbon dioxide pressure: 32 mm Hg
Partial oxygen pressure: 80 mm Hg
Lactate: 6 mmol/L
Which of the following drugs is most likely responsible for this patient’s symptoms?

(A) Acarbose
(B) Glipizide
(C) Insulin
(D) Metformin
(E) Rosiglitazone
 
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