A 62-year-old man presents to his primary care physician complaining of a recent eruption of blisters all over his body. On exam, the patient has multiple tense bullae in his axillae, groin and in flexural areas of his arms bilaterally as seen in the accompanying image. His oral exam reveals pink mucosa with no lesions. The physician takes a punch biopsy at the site of one of the blisters, which demonstrates deposits of IgG and complement along the basement membrane of the epidermis. This patient’s symptoms likely represent an autoimmune reaction targeting which of the following structures?
A. Desmosome
B. Hair Follicle
C. Hemidesmosome
D. Melanocyte
E. Pacinian corpuscle
A. Desmosome
B. Hair Follicle
C. Hemidesmosome
D. Melanocyte
E. Pacinian corpuscle