Following a course of chemotherapy, a 5-year-old male oncology patient develops altered mental status, tachycardia, decreased blood pressure, flushing

Subject
Paediatrics
System
Hematology & Oncology, Renal, Urinary Systems & Electrolytes

Kathryn

Member
Jul 29, 2020
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Singapore
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Following a course of chemotherapy, a 5-year-old male oncology patient develops altered mental status, tachycardia, decreased blood pressure, flushing of the extremities, and decreased urine output. After 48 hours in the pediatric intensive care unit, the patient dies from complications secondary to overwhelming gram-negative sepsis. At autopsy, the pathologist notes the abnormal appearance of the decedent’s kidneys, as shown in the image. What process most likely caused the findings demonstrated in the image?
1605943732731.png

(A) Acute pyelonephritis
(B) Diffuse cortical necrosis
(C) Obstructive uropathy
(D) Papillary necrosis
(E) Renal infarction
 
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