#march2020mccqe1
Haemophilus influenzae and Neisseria meningitidis both possess a polysaccharide outer capsule. Effective vaccination against these species results in the generation of antibodies that recognize this polysaccharide capsule. Which of the following best explains why the childhood vaccines for H. influenzae type B and N. meningitidis serogroup C are composed of a polysaccharide coat conjugated to a protein carrier?
(A) The protein carrier increases the half-life of the vaccine
(B) The protein carrier increases the production of IgE immunoglobulins, which confer protection
(C) The protein carrier is added to recruit T lymphocyte help and increase antibody production
(D) The protein carrier makes the vaccine less virulent and thus decreases the risk of a child developing disease from the immunization
(E) The protein carrier plays no role and is included only for ease of preparation
Haemophilus influenzae and Neisseria meningitidis both possess a polysaccharide outer capsule. Effective vaccination against these species results in the generation of antibodies that recognize this polysaccharide capsule. Which of the following best explains why the childhood vaccines for H. influenzae type B and N. meningitidis serogroup C are composed of a polysaccharide coat conjugated to a protein carrier?
(A) The protein carrier increases the half-life of the vaccine
(B) The protein carrier increases the production of IgE immunoglobulins, which confer protection
(C) The protein carrier is added to recruit T lymphocyte help and increase antibody production
(D) The protein carrier makes the vaccine less virulent and thus decreases the risk of a child developing disease from the immunization
(E) The protein carrier plays no role and is included only for ease of preparation
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