#february2020mccqe1
To assess the risk of erythroblastosis fetalis occurring during the future pregnancy of an Rh-negative woman, a clinician sends a sample of serum for detection of anti Rh-blood group antibodies. The laboratory performs an indirect Coombs’ test by mixing the patient’s serum with Rh-positive RBCs and then adding an anti-IgG antibody. In doing so, the laboratory technician observes agglutination of the RBCs. After receiving this test result, the clinician would be correct to conclude which of the following?
(A) The Coombs’ test yielded a negative result, and therefore the mother does not have anti-Rh antibodies
(B) The laboratory performed the test incorrectly; they should have mixed the patient’s serum with Rh-negative rather than Rh- positive RBCs
(C) The patient has had previous pregnancies and all of her children are Rh-negative
(D) The patient is currently pregnant with an Rh-positive fetus
(E) The presence of anti-Rh antibodies in the patient’s serum suggests that she has been pregnant with an Rh-positive fetus
To assess the risk of erythroblastosis fetalis occurring during the future pregnancy of an Rh-negative woman, a clinician sends a sample of serum for detection of anti Rh-blood group antibodies. The laboratory performs an indirect Coombs’ test by mixing the patient’s serum with Rh-positive RBCs and then adding an anti-IgG antibody. In doing so, the laboratory technician observes agglutination of the RBCs. After receiving this test result, the clinician would be correct to conclude which of the following?
(A) The Coombs’ test yielded a negative result, and therefore the mother does not have anti-Rh antibodies
(B) The laboratory performed the test incorrectly; they should have mixed the patient’s serum with Rh-negative rather than Rh- positive RBCs
(C) The patient has had previous pregnancies and all of her children are Rh-negative
(D) The patient is currently pregnant with an Rh-positive fetus
(E) The presence of anti-Rh antibodies in the patient’s serum suggests that she has been pregnant with an Rh-positive fetus
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